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Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition

Alternative splicing relies on the combinatorial recruitment of splicing regulators to specific RNA binding sites. Chromatin has been shown to impact this recruitment. However, a limited number of histone marks have been studied at a global level. In this work, a machine learning approach, applied t...

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Detalles Bibliográficos
Autores principales: Agirre, E., Oldfield, A. J., Bellora, N., Segelle, A., Luco, R. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846797/
https://www.ncbi.nlm.nih.gov/pubmed/33514745
http://dx.doi.org/10.1038/s41467-021-20979-x