Cargando…
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
Alternative splicing relies on the combinatorial recruitment of splicing regulators to specific RNA binding sites. Chromatin has been shown to impact this recruitment. However, a limited number of histone marks have been studied at a global level. In this work, a machine learning approach, applied t...
Autores principales: | Agirre, E., Oldfield, A. J., Bellora, N., Segelle, A., Luco, R. F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846797/ https://www.ncbi.nlm.nih.gov/pubmed/33514745 http://dx.doi.org/10.1038/s41467-021-20979-x |
Ejemplares similares
-
Histone Marks-Dependent Effect on Alternative Splicing: New Perspectives for Targeted Splicing Modulation in Cancer?
por: Imbriano, Carol, et al.
Publicado: (2022) -
Chromatin proteomics reveals novel combinatorial histone modification signatures that mark distinct subpopulations of macrophage enhancers
por: Soldi, Monica, et al.
Publicado: (2017) -
Overlapping splicing regulatory motifs—combinatorial effects on splicing
por: Goren, Amir, et al.
Publicado: (2010) -
Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing
por: Glaich, Ohad, et al.
Publicado: (2019) -
A chromatin code for alternative splicing involving a putative association between CTCF and HP1α proteins
por: Agirre, Eneritz, et al.
Publicado: (2015)