Infrared nanospectroscopy reveals the molecular interaction fingerprint of an aggregation inhibitor with single Aβ42 oligomers

Significant efforts have been devoted in the last twenty years to developing compounds that can interfere with the aggregation pathways of proteins related to misfolding disorders, including Alzheimer’s and Parkinson’s diseases. However, no disease-modifying drug has become available for clinical us...

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Detalles Bibliográficos
Autores principales: Ruggeri, Francesco Simone, Habchi, Johnny, Chia, Sean, Horne, Robert I., Vendruscolo, Michele, Knowles, Tuomas P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846799/
https://www.ncbi.nlm.nih.gov/pubmed/33514697
http://dx.doi.org/10.1038/s41467-020-20782-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846799/
https://www.ncbi.nlm.nih.gov/pubmed/33514697
http://dx.doi.org/10.1038/s41467-020-20782-0

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