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Stromal-driven and Amyloid β-dependent induction of neutrophil extracellular traps modulates tumor growth
Tumors consist of cancer cells and a network of non-cancerous stroma. Cancer-associated fibroblasts (CAF) are known to support tumorigenesis, and are emerging as immune modulators. Neutrophils release histone-bound nuclear DNA and cytotoxic granules as extracellular traps (NET). Here we show that CA...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846803/ https://www.ncbi.nlm.nih.gov/pubmed/33514748 http://dx.doi.org/10.1038/s41467-021-20982-2 |