Stromal-driven and Amyloid β-dependent induction of neutrophil extracellular traps modulates tumor growth

Tumors consist of cancer cells and a network of non-cancerous stroma. Cancer-associated fibroblasts (CAF) are known to support tumorigenesis, and are emerging as immune modulators. Neutrophils release histone-bound nuclear DNA and cytotoxic granules as extracellular traps (NET). Here we show that CA...

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Detalles Bibliográficos
Autores principales: Munir, Hafsa, Jones, James O., Janowitz, Tobias, Hoffmann, Markus, Euler, Maximilien, Martins, Carla P., Welsh, Sarah J., Shields, Jacqueline D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846803/
https://www.ncbi.nlm.nih.gov/pubmed/33514748
http://dx.doi.org/10.1038/s41467-021-20982-2

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