Cargando…

Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure

Heart failure (HF) occurs frequently among older individuals, and dysfunction of cardiac mitochondria is often observed. We here show the cardiac-specific downregulation of a certain mitochondrial component during the chronological aging of mice, which is detrimental to the heart. MitoNEET is a mito...

Descripción completa

Detalles Bibliográficos
Autores principales: Furihata, Takaaki, Takada, Shingo, Kakutani, Naoya, Maekawa, Satoshi, Tsuda, Masaya, Matsumoto, Junichi, Mizushima, Wataru, Fukushima, Arata, Yokota, Takashi, Enzan, Nobuyuki, Matsushima, Shouji, Handa, Haruka, Fumoto, Yoshizuki, Nio-Kobayashi, Junko, Iwanaga, Toshihiko, Tanaka, Shinya, Tsutsui, Hiroyuki, Sabe, Hisataka, Kinugawa, Shintaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846856/
https://www.ncbi.nlm.nih.gov/pubmed/33514783
http://dx.doi.org/10.1038/s42003-021-01675-4