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Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure
Heart failure (HF) occurs frequently among older individuals, and dysfunction of cardiac mitochondria is often observed. We here show the cardiac-specific downregulation of a certain mitochondrial component during the chronological aging of mice, which is detrimental to the heart. MitoNEET is a mito...
Autores principales: | Furihata, Takaaki, Takada, Shingo, Kakutani, Naoya, Maekawa, Satoshi, Tsuda, Masaya, Matsumoto, Junichi, Mizushima, Wataru, Fukushima, Arata, Yokota, Takashi, Enzan, Nobuyuki, Matsushima, Shouji, Handa, Haruka, Fumoto, Yoshizuki, Nio-Kobayashi, Junko, Iwanaga, Toshihiko, Tanaka, Shinya, Tsutsui, Hiroyuki, Sabe, Hisataka, Kinugawa, Shintaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846856/ https://www.ncbi.nlm.nih.gov/pubmed/33514783 http://dx.doi.org/10.1038/s42003-021-01675-4 |
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