Response Surface Optimization of Ultra-Elastic Nanovesicles Loaded with Deflazacort Tailored for Transdermal Delivery: Accentuated Bioavailability and Anti-Inflammatory Efficacy

PURPOSE: The aim of the present study was to develop deflazacort (DFZ) ultra-elastic nanovesicles (UENVs) loaded gel for topical administration to evade gastrointestinal adverse impacts accompanying DFZ oral therapy. METHODS: UENVs were elaborated according to D-optimal mixture design employing diff...

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Detalles Bibliográficos
Autores principales: Ali, Adel A, Hassan, Amira H, Eissa, Essam M, Aboud, Heba M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846863/
https://www.ncbi.nlm.nih.gov/pubmed/33531803
http://dx.doi.org/10.2147/IJN.S276330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846863/
https://www.ncbi.nlm.nih.gov/pubmed/33531803
http://dx.doi.org/10.2147/IJN.S276330

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