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MicroRNA-130a Is Elevated in Thyroid Eye Disease and Increases Lipid Accumulation in Fibroblasts Through the Suppression of AMPK
PURPOSE: Thyroid eye disease (TED) is a condition that causes the tissue behind the eye to become inflamed and can result in excessive fatty tissue accumulation in the orbit. Two subpopulations of fibroblasts reside in the orbit: those that highly express Thy1 (Thy1+) and those with little or no Thy...
Autores principales: | Hammond, Christine L., Roztocil, Elisa, Gonzalez, Mithra O., Feldon, Steven E., Woeller, Collynn F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846950/ https://www.ncbi.nlm.nih.gov/pubmed/33507228 http://dx.doi.org/10.1167/iovs.62.1.29 |
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