Downregulation of Retinal Connexin 43 in GFAP-Expressing Cells Modifies Vasoreactivity Induced by Perfusion Ocular Pressure Changes

PURPOSE: Glia and their communication via connexin 43 (Cx43) gap junctions are known to mediate neurovascular coupling, a process driven by metabolic demand. However, it is unclear whether Cx43 mediated glial communication intermediates classical autoregulation. Here we used viral transfection and a...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Guodong, Li, Hui, Cull, Grant, Wilsey, Laura, Yang, Hongli, Reemmer, Jesica, Shen, Hai-Ying, Wang, Fang, Fortune, Brad, Bui, Bang V., Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Physiology and Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846954/
https://www.ncbi.nlm.nih.gov/pubmed/33502459
http://dx.doi.org/10.1167/iovs.62.1.26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846954/
https://www.ncbi.nlm.nih.gov/pubmed/33502459
http://dx.doi.org/10.1167/iovs.62.1.26

Ejemplares similares