Pharmacokinetics and dialytic clearance of apixaban during in vitro continuous renal replacement therapy

BACKGROUND: To evaluate the transmembrane clearance (CL(TM)) of apixaban during modeled in vitro continuous renal replacement therapy (CRRT), assess protein binding and circuit adsorption, and provide initial dosing recommendations. METHODS: Apixaban was added to the CRRT circuit and serial pre-filt...

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Detalles Bibliográficos
Autores principales: Andrews, Lauren, Benken, Scott, Tan, Xing, Wenzler, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847018/
https://www.ncbi.nlm.nih.gov/pubmed/33516188
http://dx.doi.org/10.1186/s12882-021-02248-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847018/
https://www.ncbi.nlm.nih.gov/pubmed/33516188
http://dx.doi.org/10.1186/s12882-021-02248-7

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