Polysaccharide from Angelica sinensis attenuates SNP-induced apoptosis in osteoarthritis chondrocytes by inducing autophagy via the ERK1/2 pathway

OBJECTIVE: Chondrocyte apoptosis plays a vital role in osteoarthritis (OA) progression. Angelica sinensis polysaccharide (ASP), a traditional Chinese medicine, possesses anti-inflammatory and anti-apoptotic properties in chondrocytes. This study aimed to determine the protective role of ASP on sodiu...

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Detalles Bibliográficos
Autores principales: Xu, Chao, Ni, Su, Zhuang, Chao, Li, Chenkai, Zhao, Gongyin, Jiang, Shijie, Wang, Liangliang, Zhu, Ruixia, van Wijnen, Andre J., Wang, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847159/
https://www.ncbi.nlm.nih.gov/pubmed/33514407
http://dx.doi.org/10.1186/s13075-020-02409-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847159/
https://www.ncbi.nlm.nih.gov/pubmed/33514407
http://dx.doi.org/10.1186/s13075-020-02409-3

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