Cargando…
Polysaccharide from Angelica sinensis attenuates SNP-induced apoptosis in osteoarthritis chondrocytes by inducing autophagy via the ERK1/2 pathway
OBJECTIVE: Chondrocyte apoptosis plays a vital role in osteoarthritis (OA) progression. Angelica sinensis polysaccharide (ASP), a traditional Chinese medicine, possesses anti-inflammatory and anti-apoptotic properties in chondrocytes. This study aimed to determine the protective role of ASP on sodiu...
Autores principales: | Xu, Chao, Ni, Su, Zhuang, Chao, Li, Chenkai, Zhao, Gongyin, Jiang, Shijie, Wang, Liangliang, Zhu, Ruixia, van Wijnen, Andre J., Wang, Yuji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847159/ https://www.ncbi.nlm.nih.gov/pubmed/33514407 http://dx.doi.org/10.1186/s13075-020-02409-3 |
Ejemplares similares
-
Oxidative Stress Induces Chondrocyte Apoptosis through Caspase-Dependent and Caspase-Independent Mitochondrial Pathways and the Antioxidant Mechanism of Angelica Sinensis Polysaccharide
por: Zhuang, Chao, et al.
Publicado: (2020) -
Theaflavin-3,3′-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis
por: Xu, Chao, et al.
Publicado: (2022) -
Angelica sinensis polysaccharide (ASP) attenuates diosbulbin-B (DB)-induced hepatotoxicity through activating the MEK/ERK pathway
por: Li, Chunfeng, et al.
Publicado: (2021) -
Effect of Angelica sinensis Polysaccharides on Osteoarthritis In Vivo and In Vitro: A Possible Mechanism to Promote Proteoglycans Synthesis
por: Qin, Jun, et al.
Publicado: (2013) -
Protective potential of Angelica sinensis polysaccharide extract against ethylene glycol-induced calcium oxalate urolithiasis
por: Wang, Shengbao, et al.
Publicado: (2018)