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SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses

BACKGROUND: Upon SARS-CoV-2 infection, most individuals develop neutralizing antibodies and T-cell immunity. However, some individuals reportedly remain SARS-CoV-2 PCR positive by pharyngeal swabs weeks after recovery. Whether viral RNA in these persistent carriers is contagious and stimulates SARS-...

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Detalles Bibliográficos
Autores principales: Vibholm, Line K, Nielsen, Stine SF, Pahus, Marie H, Frattari, Giacomo S, Olesen, Rikke, Andersen, Rebecca, Monrad, Ida, Andersen, Anna HF, Thomsen, Michelle M, Konrad, Christina V, Andersen, Sidsel D, Højen, Jesper F, Gunst, Jesper D, Østergaard, Lars, Søgaard, Ole S, Schleimann, Mariane H, Tolstrup, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847186/
https://www.ncbi.nlm.nih.gov/pubmed/33530000
http://dx.doi.org/10.1016/j.ebiom.2021.103230