Exploring a model-based analysis of patient derived xenograft studies in oncology drug development

PURPOSE: To assess whether a model-based analysis increased statistical power over an analysis of final day volumes and provide insights into more efficient patient derived xenograft (PDX) study designs. METHODS: Tumour xenograft time-series data was extracted from a public PDX drug treatment databa...

Descripción completa

Detalles Bibliográficos
Autores principales: Dickinson, Jake, de Matas, Marcel, Dickinson, Paul A., Mistry, Hitesh B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Drugs and Devices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847196/
https://www.ncbi.nlm.nih.gov/pubmed/33569251
http://dx.doi.org/10.7717/peerj.10681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847196/
https://www.ncbi.nlm.nih.gov/pubmed/33569251
http://dx.doi.org/10.7717/peerj.10681

Ejemplares similares