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Cost-Effective Trap qPCR Approach to Evaluate Telomerase Activity: an Important Tool for Aging, Cancer, and Chronic Disease Research

OBJECTIVES: Telomeres are a terminal “DNA cap” that prevent chromosomal fusion and degradation. However, aging is inherent to life, and so is the loss of terminal sequences. Telomerase is a specialized reverse transcriptase encoded by self-splicing introns that counteract chromosome erosion. Telomer...

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Detalles Bibliográficos
Autores principales: Pinto, Thalyta Nery Carvalho, Fernandes, Juliana Ruiz, Arruda, Liã Barbara, Duarte, Alberto José da Silva, Benard, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Medicina / USP 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847253/
https://www.ncbi.nlm.nih.gov/pubmed/33567048
http://dx.doi.org/10.6061/clinics/2021/e2432