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Cost-Effective Trap qPCR Approach to Evaluate Telomerase Activity: an Important Tool for Aging, Cancer, and Chronic Disease Research
OBJECTIVES: Telomeres are a terminal “DNA cap” that prevent chromosomal fusion and degradation. However, aging is inherent to life, and so is the loss of terminal sequences. Telomerase is a specialized reverse transcriptase encoded by self-splicing introns that counteract chromosome erosion. Telomer...
Autores principales: | Pinto, Thalyta Nery Carvalho, Fernandes, Juliana Ruiz, Arruda, Liã Barbara, Duarte, Alberto José da Silva, Benard, Gil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculdade de Medicina / USP
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847253/ https://www.ncbi.nlm.nih.gov/pubmed/33567048 http://dx.doi.org/10.6061/clinics/2021/e2432 |
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