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Treatment with therapeutic anticoagulation is not associated with immunotherapy response in advanced cancer patients

BACKGROUND: Recent preclinical data suggest that there may be therapeutic synergy between immune checkpoint blockade and inhibition of the coagulation cascade. Here, we investigate whether patients who received immune checkpoint inhibitors (ICI) and were on concomitant anticoagulation (AC) experienc...

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Detalles Bibliográficos
Autores principales: Johannet, Paul, Sawyers, Amelia, Gulati, Nicholas, Donnelly, Douglas, Kozloff, Samuel, Qian, Yingzhi, Floristan, Alfredo, Hernando, Eva, Zhong, Judy, Osman, Iman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847556/
https://www.ncbi.nlm.nih.gov/pubmed/33516263
http://dx.doi.org/10.1186/s12967-021-02712-w