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A pharmacogenetics study of platinum-based chemotherapy in lung cancer: ABCG2 polymorphism and its genetic interaction with SLC31A1 are associated with response and survival

Objective: The expression and function of platinum transporters affect drug tissue concentration and therapeutic effects. We had previously characterized functional variant of platinum intake transporter SLC31A1 gene. We aimed to investigate the association of platinum efflux transporter gene ABCG2...

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Detalles Bibliográficos
Autores principales: Wang, Liyan, Sun, Chang, Li, Xiangnan, Mao, Chenxue, Qian, Ji, Wang, Jiucun, Wu, Junjie, Li, Qiang, Bai, Chunxue, Han, Baohui, Gao, Zhiqiang, Xu, Jibin, Yin, Jiye, Liu, Zhaoqian, Lu, Daru, Jin, Li, Wang, Haijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847637/
https://www.ncbi.nlm.nih.gov/pubmed/33531973
http://dx.doi.org/10.7150/jca.51621