The COL11A1/Akt/CREB signaling axis enables mitochondrial-mediated apoptotic evasion to promote chemoresistance in pancreatic cancer cells through modulating BAX/BCL-2 function

Collagen XI, a member of the collagen family, is present in the extracellular matrix (ECM), and high collagen XI/αI (COL11A1) expression in tumor tissue is reportedly correlated with the clinicopathological parameters of pancreatic ductal adenocarcinoma (PDAC). However, the function of COL11A1 in th...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Ren, Runling, Yang, Zizhong, Cai, Jun, Du, Shaoxia, Shen, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847647/
https://www.ncbi.nlm.nih.gov/pubmed/33531986
http://dx.doi.org/10.7150/jca.47032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847647/
https://www.ncbi.nlm.nih.gov/pubmed/33531986
http://dx.doi.org/10.7150/jca.47032

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