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Abraxane-induced bone marrow CD11b(+) myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with (64)Cu-labeled anti-CD11b and prevented by anti-CSF-1
To investigate the utility of noninvasive µPET-CT with (64)Cu-DOTA-anti-CD11b ((64)Cu-αCD11b) in assessing bone marrow status after anticancer therapies, and the protective role of anti-CSF-1 (αCSF-1) against bone marrow suppression induced by Abraxane. Methods: MDA-MB-435 tumor-bearing mice were tr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847669/ https://www.ncbi.nlm.nih.gov/pubmed/33537102 http://dx.doi.org/10.7150/thno.49421 |