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Honokiol/Magnolol-Loaded Self-Assembling Lecithin-Based Mixed Polymeric Micelles (lbMPMs) for Improving Solubility to Enhance Oral Bioavailability

OBJECTIVE: This study was intended to utilize lecithin-based mixed polymeric micelles (lbMPMs) for enhancing the solubility and bioavailability of honokiol and magnolol to resolve the hindrance of their extreme hydrophobicity on the clinical applications. METHODS: Lecithin was selected to increase t...

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Detalles Bibliográficos
Autores principales: Lin, Hong-Liang, Cheng, Wen-Ting, Chen, Ling-Chun, Ho, Hsiu-O, Lin, Shyr-Yi, Hsieh, Chien-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847769/
https://www.ncbi.nlm.nih.gov/pubmed/33536753
http://dx.doi.org/10.2147/IJN.S290444