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HMGA1 Induction of miR-103/107 Forms a Negative Feedback Loop to Regulate Autophagy in MPTP Model of Parkinson’s Disease

Autophagy dysfunction has been directly linked with the onset and progression of Parkinson’s disease (PD), but the underlying mechanisms are not well understood. High-mobility group A1 (HMGA1), well-known chromatin remodeling proteins, play pivotal roles in diverse biological processes and diseases....

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Detalles Bibliográficos
Autores principales: Li, Gehui, Luo, Wanxian, Wang, Baoyan, Qian, Chen, Ye, Yongyi, Li, Yuantao, Zhang, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847849/
https://www.ncbi.nlm.nih.gov/pubmed/33536877
http://dx.doi.org/10.3389/fncel.2020.620020