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Voluntary activity reverses spermidine-induced myocardial fibrosis and lipid accumulation in the obese male mouse
Obesity due to high calorie intake induces cardiac hypertrophy and dysfunction, thus contributing to cardiovascular morbidity and mortality. Recent studies in aging suggest that oral supplementation with the natural polyamine spermidine has a cardioprotective effect. Here, the hypothesis was tested...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847856/ https://www.ncbi.nlm.nih.gov/pubmed/33108533 http://dx.doi.org/10.1007/s00418-020-01926-1 |