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Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens
Tumors with an impaired transporter associated with antigen processing (TAP) present several endoplasmic reticulum-derived self-antigens on HLA class I (HLA-I) which are absent on healthy cells. Selection of such TAP-independent antigens for T cell-based immunotherapy should include analysis of thei...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847959/ https://www.ncbi.nlm.nih.gov/pubmed/33554062 http://dx.doi.org/10.1016/j.isci.2021.102051 |