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Essential Role of IFN-γ in Regulating Gut Antimicrobial Peptides and Microbiota to Protect Against Alcohol-Induced Bacterial Translocation and Hepatic Inflammation in Mice

The mechanisms by which alcohol provokes bacterial translocation in the development of alcoholic liver disease (ALD) remain incompletely defined. Our previous study demonstrates that impaired gut epithelial antimicrobial defense is critically involved in the pathogenesis of ALD. The study was set to...

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Detalles Bibliográficos
Autores principales: Yue, Ruichao, Wei, Xiaoyuan, Zhao, Jiangchao, Zhou, Zhanxiang, Zhong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848155/
https://www.ncbi.nlm.nih.gov/pubmed/33536944
http://dx.doi.org/10.3389/fphys.2020.629141