PAR2 Inhibition Enhanced the Sensitivity of Colorectal Cancer Cells to 5-FU and Reduced EMT Signaling

The aim of this study was to investigate the underlying mechanisms that transforming growth factor-β (TGF-β)-mediated epithelial-to-mesenchymal transition (EMT) in tumor cells contributes to 5-FU resistance. A series of experiments involving cell viability and caspase activity analyses, siRNA transf...

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Detalles Bibliográficos
Autores principales: Quan, Qiuying, Zhong, Fengyun, Wang, Xinwei, Chen, Kai, Guo, Lingchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848255/
https://www.ncbi.nlm.nih.gov/pubmed/30841957
http://dx.doi.org/10.3727/096504018X15442985680348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848255/
https://www.ncbi.nlm.nih.gov/pubmed/30841957
http://dx.doi.org/10.3727/096504018X15442985680348

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