FCY-302, a Novel Small Molecule, Induces Apoptosis in Leukemia and Myeloma Cells by Attenuating Key Antioxidant and Mitochondrial Enzymes

Arylidene analogs are well proven for biological activities. FCY-302, a novel small molecule belonging to this class, was screened for its biological efficacy in leukemia and myeloma cells. FCY-302 selectively inhibited proliferation of cancer cells with GI(50) values of 395.2 nM, 514.6 Nm, and 642....

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Detalles Bibliográficos
Autores principales: Rajagopalan, Prasanna, Hakami, Abdulrahim, Ragab, Mohammed, Elbessoumy, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848260/
https://www.ncbi.nlm.nih.gov/pubmed/31046873
http://dx.doi.org/10.3727/096504019X15555428221646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848260/
https://www.ncbi.nlm.nih.gov/pubmed/31046873
http://dx.doi.org/10.3727/096504019X15555428221646

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