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Nutlin-3-Induced Sensitization of Non-Small Cell Lung Cancer Stem Cells to Axitinib-Induced Apoptosis Through Repression of Akt1/Wnt Signaling

The aim of this study was to investigate the potential biological activities of nutlin-3 in the regulation of growth and proliferation of non-small cell lung cancer (NSCLC) stem cells (CSCs), which may help in sensitizing to axitinib-induced apoptosis. Nutlin-3 induction of p53 expression was used t...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Wang, Xin, Li, Yuan, Xiao, Qiang, Cui, Xiao-Hai, Xiao, Guo-Dong, Wang, Ji-Chang, Xu, Chong-Wen, Ren, Hong, Liu, Dapeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848271/
https://www.ncbi.nlm.nih.gov/pubmed/30832755
http://dx.doi.org/10.3727/096504018X15424918479652