NOTCH3 Overexpression and Posttranscriptional Regulation by miR-150 Were Associated With EGFR–TKI Resistance in Lung Adenocarcinoma

Acquired resistance remains a key challenge in epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors (TKIs) therapy in lung adenocarcinoma (LUAD). Recent studies have shown that Notch signaling is associated with drug resistance. However, its role and possible mechanisms in EGFR-TKI res...

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Detalles Bibliográficos
Autores principales: Zhang, Youwei, Chen, Bi, Wang, Yongsheng, Zhao, Qi, Wu, Weijun, Zhang, Peiying, Miao, Liyun, Sun, Sanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848279/
https://www.ncbi.nlm.nih.gov/pubmed/30732676
http://dx.doi.org/10.3727/096504018X15372657298381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848279/
https://www.ncbi.nlm.nih.gov/pubmed/30732676
http://dx.doi.org/10.3727/096504018X15372657298381

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