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NOTCH3 Overexpression and Posttranscriptional Regulation by miR-150 Were Associated With EGFR–TKI Resistance in Lung Adenocarcinoma
Acquired resistance remains a key challenge in epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors (TKIs) therapy in lung adenocarcinoma (LUAD). Recent studies have shown that Notch signaling is associated with drug resistance. However, its role and possible mechanisms in EGFR-TKI res...
Autores principales: | Zhang, Youwei, Chen, Bi, Wang, Yongsheng, Zhao, Qi, Wu, Weijun, Zhang, Peiying, Miao, Liyun, Sun, Sanyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cognizant Communication Corporation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848279/ https://www.ncbi.nlm.nih.gov/pubmed/30732676 http://dx.doi.org/10.3727/096504018X15372657298381 |
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