Silencing of NADPH Oxidase 4 Attenuates Hypoxia Resistance in Neuroblastoma Cells SH-SY5Y by Inhibiting PI3K/Akt-Dependent Glycolysis

Hypoxia-induced chemoresistance is a major obstacle in the development of effective cancer therapy. In our study, the reversal abilities of NADPH oxidase 4 (NOX4) silence on hypoxia resistance and the potential mechanism were investigated. Our data showed that the expression of NOX4 was upregulated...

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Detalles Bibliográficos
Autores principales: Yu, Ting, Li, Lei, Liu, Wenyan, Ya, Bailiu, Cheng, Hongju, Xin, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848326/
https://www.ncbi.nlm.nih.gov/pubmed/29426376
http://dx.doi.org/10.3727/096504018X15179668157803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848326/
https://www.ncbi.nlm.nih.gov/pubmed/29426376
http://dx.doi.org/10.3727/096504018X15179668157803

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