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PD-L1 Induces Epithelial–Mesenchymal Transition in Nasopharyngeal Carcinoma Cells Through Activation of the PI3K/AKT Pathway

Nasopharyngeal cancer (NPC) is a malignant epithelial carcinoma of the head and neck. Cancer therapy targeting programmed cell death protein-1 (PD-1) or programmed death ligand-1 (PD-L1) is revolutionary. However, the tumorigenic mechanism of PD-L1 is not yet clear in NPC. Here we demonstrated an on...

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Detalles Bibliográficos
Autores principales: Fei, Zhenghua, Deng, Zhenxiang, Zhou, Lingyang, Li, Kejie, Xia, Xiaofang, Xie, Raoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848446/
https://www.ncbi.nlm.nih.gov/pubmed/30982497
http://dx.doi.org/10.3727/096504018X15446984186056