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Ursolic Acid Attenuates TGF-β1-Induced Epithelial–Mesenchymal Transition in NSCLC by Targeting Integrin αVβ5/MMPs Signaling

Transforming growth factor-β1 (TGF-β1)-induced epithelial–mesenchymal transition (EMT) of non-small cell lung cancer (NSCLC) may contribute to tumor metastasis. TGF-β1-induced EMT in H1975 cells (a human NSCLC cell line) resulted in the adoption of mesenchymal responses that were predominantly media...

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Detalles Bibliográficos
Autores principales: Ruan, Jun Shan, Zhou, Huan, Yang, Lin, Wang, Ling, Jiang, Zong Sheng, Sun, Hong, Wang, Shao Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848462/
https://www.ncbi.nlm.nih.gov/pubmed/28911340
http://dx.doi.org/10.3727/096504017X15051723858706