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Evolution in the weak-mutation limit: Stasis periods punctuated by fast transitions between saddle points on the fitness landscape

A mathematical analysis of the evolution of a large population under the weak-mutation limit shows that such a population would spend most of the time in stasis in the vicinity of saddle points on the fitness landscape. The periods of stasis are punctuated by fast transitions, in lnN(e)/s time (N(e)...

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Detalles Bibliográficos
Autores principales: Bakhtin, Yuri, Katsnelson, Mikhail I., Wolf, Yuri I., Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848522/
https://www.ncbi.nlm.nih.gov/pubmed/33472973
http://dx.doi.org/10.1073/pnas.2015665118