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In-silico human electro-mechanical ventricular modelling and simulation for drug-induced pro-arrhythmia and inotropic risk assessment

Human-based computational modelling and simulation are powerful tools to accelerate the mechanistic understanding of cardiac patho-physiology, and to develop and evaluate therapeutic interventions. The aim of this study is to calibrate and evaluate human ventricular electro-mechanical models for inv...

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Detalles Bibliográficos
Autores principales: Margara, Francesca, Wang, Zhinuo J., Levrero-Florencio, Francesc, Santiago, Alfonso, Vázquez, Mariano, Bueno-Orovio, Alfonso, Rodriguez, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848595/
https://www.ncbi.nlm.nih.gov/pubmed/32710902
http://dx.doi.org/10.1016/j.pbiomolbio.2020.06.007