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Self-assembled nanostructures of L-ascorbic acid alkyl esters support monomeric amphotericin B

HYPOTHESIS: Amphotericin B (AmB) is a highly effective antimicrobial, with broad antimycotic and antiparasitic effect. However, AmB poor water-solubilisation and aggregation tendency limits its use for topical applications. We studied the capacity of nanostructures formed by alkyl esters of L-ascorb...

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Detalles Bibliográficos
Autores principales: Nocelli, Natalia E., Zulueta Díaz, Yenisleidy de las Mercedes, Millot, Marine, Colazo, María Luz, Vico, Raquel V., Fanani, Maria Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848660/
https://www.ncbi.nlm.nih.gov/pubmed/33553743
http://dx.doi.org/10.1016/j.heliyon.2021.e06056