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Immunogenicity Challenges Associated with Subcutaneous Delivery of Therapeutic Proteins

The subcutaneous route of administration has provided convenient and non-inferior delivery of therapeutic proteins compared to intravenous infusion, but there is potential for enhanced immunogenicity toward subcutaneously administered proteins in a subset of patients. Unwanted anti-drug antibody res...

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Detalles Bibliográficos
Autores principales: Jarvi, Nicole L., Balu-Iyer, Sathy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848667/
https://www.ncbi.nlm.nih.gov/pubmed/33523413
http://dx.doi.org/10.1007/s40259-020-00465-4