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Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases

The reversibility of ubiquitination by the action of deubiquitinating enzymes (DUBs) serves as an important regulatory layer within the ubiquitin system. Approximately 100 DUBs are encoded by the human genome, and many have been implicated with pathologies, including neurodegeneration and cancer. No...

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Detalles Bibliográficos
Autores principales: De Cesare, Virginia, Carbajo Lopez, Daniel, Mabbitt, Peter D., Fletcher, Adam J., Soetens, Mathieu, Antico, Odetta, Wood, Nicola T., Virdee, Satpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848729/
https://www.ncbi.nlm.nih.gov/pubmed/33479176
http://dx.doi.org/10.1073/pnas.2006947118