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Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases
The reversibility of ubiquitination by the action of deubiquitinating enzymes (DUBs) serves as an important regulatory layer within the ubiquitin system. Approximately 100 DUBs are encoded by the human genome, and many have been implicated with pathologies, including neurodegeneration and cancer. No...
Autores principales: | De Cesare, Virginia, Carbajo Lopez, Daniel, Mabbitt, Peter D., Fletcher, Adam J., Soetens, Mathieu, Antico, Odetta, Wood, Nicola T., Virdee, Satpal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848729/ https://www.ncbi.nlm.nih.gov/pubmed/33479176 http://dx.doi.org/10.1073/pnas.2006947118 |
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