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Visceral adipose tissue-directed FGF21 gene therapy improves metabolic and immune health in BTBR mice

Fibroblast growth factor 21 (FGF21) is a peptide hormone that serves as a potent effector of energy homeostasis. Increasingly, FGF21 is viewed as a promising therapeutic agent for type 2 diabetes, fatty liver disease, and other metabolic complications. Exogenous administration of native FGF21 peptid...

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Detalles Bibliográficos
Autores principales: Queen, Nicholas J., Bates, Rhiannon, Huang, Wei, Xiao, Run, Appana, Bhavya, Cao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848733/
https://www.ncbi.nlm.nih.gov/pubmed/33575433
http://dx.doi.org/10.1016/j.omtm.2020.12.011