Cargando…

The ESCRT machinery regulates retromer-dependent transcytosis of septate junction components in Drosophila

Loss of ESCRT function in Drosophila imaginal discs is known to cause neoplastic overgrowth fueled by mis-regulation of signaling pathways. Its impact on junctional integrity, however, remains obscure. To dissect the events leading to neoplasia, we used transmission electron microscopy (TEM) on wing...

Descripción completa

Detalles Bibliográficos
Autores principales: Pannen, Hendrik, Rapp, Tim, Klein, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848756/
https://www.ncbi.nlm.nih.gov/pubmed/33377869
http://dx.doi.org/10.7554/eLife.61866