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The ESCRT machinery regulates retromer-dependent transcytosis of septate junction components in Drosophila

Loss of ESCRT function in Drosophila imaginal discs is known to cause neoplastic overgrowth fueled by mis-regulation of signaling pathways. Its impact on junctional integrity, however, remains obscure. To dissect the events leading to neoplasia, we used transmission electron microscopy (TEM) on wing...

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Detalles Bibliográficos
Autores principales: Pannen, Hendrik, Rapp, Tim, Klein, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848756/
https://www.ncbi.nlm.nih.gov/pubmed/33377869
http://dx.doi.org/10.7554/eLife.61866

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