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Automated mesenchymal stem cell segmentation and machine learning-based phenotype classification using morphometric and textural analysis

Purpose: Mesenchymal stem cells (MSCs) have demonstrated clinically relevant therapeutic effects for treatment of trauma and chronic diseases. The proliferative potential, immunomodulatory characteristics, and multipotentiality of MSCs in monolayer culture is reflected by their morphological phenoty...

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Detalles Bibliográficos
Autores principales: Mota, Sakina M., Rogers, Robert E., Haskell, Andrew W., McNeill, Eoin P., Kaunas, Roland, Gregory, Carl A., Giger, Maryellen L., Maitland, Kristen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849042/
https://www.ncbi.nlm.nih.gov/pubmed/33542945
http://dx.doi.org/10.1117/1.JMI.8.1.014503