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Pan-cancer detection of driver genes at the single-patient resolution

BACKGROUND: Identifying the complete repertoire of genes that drive cancer in individual patients is crucial for precision oncology. Most established methods identify driver genes that are recurrently altered across patient cohorts. However, mapping these genes back to patients leaves a sizeable fra...

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Detalles Bibliográficos
Autores principales: Nulsen, Joel, Misetic, Hrvoje, Yau, Christopher, Ciccarelli, Francesca D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849133/
https://www.ncbi.nlm.nih.gov/pubmed/33517897
http://dx.doi.org/10.1186/s13073-021-00830-0