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Pan-cancer detection of driver genes at the single-patient resolution
BACKGROUND: Identifying the complete repertoire of genes that drive cancer in individual patients is crucial for precision oncology. Most established methods identify driver genes that are recurrently altered across patient cohorts. However, mapping these genes back to patients leaves a sizeable fra...
Autores principales: | Nulsen, Joel, Misetic, Hrvoje, Yau, Christopher, Ciccarelli, Francesca D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849133/ https://www.ncbi.nlm.nih.gov/pubmed/33517897 http://dx.doi.org/10.1186/s13073-021-00830-0 |
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