Opioid therapy duration before naldemedine treatment is a significant independent risk of diarrhea: a retrospective cohort study

BACKGROUND: The most common adverse event (AE) associated with opioid analgesics is opioid-induced constipation (OIC). Naldemedine (NAL) is widely used for the treatment of OIC. However, diarrhea has been reported as the most common treatment-emergent AE of NAL, and little is known about the risk fa...

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Detalles Bibliográficos
Autores principales: Okamoto, Akiharu, Ikemura, Kenji, Mizutani, Eri, Iwamoto, Takuya, Okuda, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849155/
https://www.ncbi.nlm.nih.gov/pubmed/33517900
http://dx.doi.org/10.1186/s40780-020-00187-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849155/
https://www.ncbi.nlm.nih.gov/pubmed/33517900
http://dx.doi.org/10.1186/s40780-020-00187-3

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