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Architecture of the active post‐translational Sec translocon

In eukaryotes, most secretory and membrane proteins are targeted by an N‐terminal signal sequence to the endoplasmic reticulum, where the trimeric Sec61 complex serves as protein‐conducting channel (PCC). In the post‐translational mode, fully synthesized proteins are recognized by a specialized chan...

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Detalles Bibliográficos
Autores principales: Weng, Tsai‐Hsuan, Steinchen, Wieland, Beatrix, Birgitta, Berninghausen, Otto, Becker, Thomas, Bange, Gert, Cheng, Jingdong, Beckmann, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849165/
https://www.ncbi.nlm.nih.gov/pubmed/33305433
http://dx.doi.org/10.15252/embj.2020105643