Cargando…
Architecture of the active post‐translational Sec translocon
In eukaryotes, most secretory and membrane proteins are targeted by an N‐terminal signal sequence to the endoplasmic reticulum, where the trimeric Sec61 complex serves as protein‐conducting channel (PCC). In the post‐translational mode, fully synthesized proteins are recognized by a specialized chan...
Autores principales: | Weng, Tsai‐Hsuan, Steinchen, Wieland, Beatrix, Birgitta, Berninghausen, Otto, Becker, Thomas, Bange, Gert, Cheng, Jingdong, Beckmann, Roland |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849165/ https://www.ncbi.nlm.nih.gov/pubmed/33305433 http://dx.doi.org/10.15252/embj.2020105643 |
Ejemplares similares
-
Partially inserted nascent chain unzips the lateral gate of the Sec translocon
por: Kater, Lukas, et al.
Publicado: (2019) -
Cryo–EM structure of the ribosome–SecYE complex in the membrane environment
por: Frauenfeld, Jens, et al.
Publicado: (2011) -
The Dynamic SecYEG Translocon
por: Oswald, Julia, et al.
Publicado: (2021) -
The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains
por: Knorr, Alexandra G., et al.
Publicado: (2023) -
Unlocking the Bacterial SecY Translocon
por: Corey, Robin A., et al.
Publicado: (2016)