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Netrin‐1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson’s disease features

The netrin‐1/DCC ligand/receptor pair has key roles in central nervous system (CNS) development, mediating axonal, and neuronal navigation. Although expression of netrin‐1 and DCC is maintained in the adult brain, little is known about their role in mature neurons. Notably, netrin‐1 is highly expres...

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Detalles Bibliográficos
Autores principales: Jasmin, Mélissa, Ahn, Eun Hee, Voutilainen, Merja H, Fombonne, Joanna, Guix, Catherine, Viljakainen, Tuulikki, Kang, Seong Su, Yu, Li‐ying, Saarma, Mart, Mehlen, Patrick, Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849168/
https://www.ncbi.nlm.nih.gov/pubmed/33351190
http://dx.doi.org/10.15252/embj.2020105537